DDIWAS R package

Introduction

Use this R package to perform Drug-Drug Interaction Wide Association Study (DDIWAS) experiments with electronic health record (EHR) data.

Installation

To install the latest development version directly from GitHub, use:

#Install required packages
install.packages(c("devtools","tidyverse","broom","glue","varhandle","logistf"))

devtools::install_github("pwatrick/ddiwas")

User Documentation

• Documentation can be found on the package website.
  
• Learn to extract EHR data for DDIWAS vignette.
  
• Learn to use the DDIWAS R package to process EHR data and statistical analysis vignette.

License

Apache License 2.0

Development

This package was developed in RStudio.

Development status

This package is ready for use.

Citation

Patrick Wu, Scott D Nelson, Juan Zhao, Cosby A Stone Jr, QiPing Feng, Qingxia Chen, Eric A Larson, Bingshan Li, Nancy J Cox, C Michael Stein, Elizabeth J Phillips, Dan M Roden, Joshua C Denny, Wei-Qi Wei, DDIWAS: High-throughput electronic health record-based screening of drug-drug interactions, Journal of the American Medical Informatics Association, Volume 28, Issue 7, July 2021, Pages 1421–1430, https://doi.org/10.1093/jamia/ocab019